Dr Christine White is a post-doctoral researcher at the Department of Histopathology Trinity College Dublin/Coombe Women and Infants University Hospital, Dublin. Following an undergraduate degree in Medical Molecular Cytology at the Dublin Institute of Technology, Christine completed a PhD with CERVIVA investigated the utility of biomarkers in cervical screening. Christine went on to work on a 7th framework funded programme, SYSTEMCERV, which identified new biomarkers for cervical pre-cancer and cancer. She is now working on the HPV Primary Screening Study. The Primary Screening study will explore the use human papillomavirus (HPV) testing as a first-line screening method. The study is based on research that indicates that using HPV testing as the initial screen can better indicate which women are at risk of potentially cancerous lesions compared with using PAP tests. Research has shown that HPV testing can detect more cervical cell abnormalities than the traditional PAP test. Furthermore women who do not have HPV have a greater degree of reassurance that they will not develop cancer. The presence of HPV does not always lead to the development of cervical cancer. To ensure HPV testing is effective, we need to find out which HPV positive samples are likely to develop into cancer. To do this, we will look into samples that test positive for HPV in a little more detail. We will do additional tests to look for specific markers that we know are linked to HPV infection. By following women to see what happens over the course of several smear tests we will be able to determine how useful these new approaches to cervical screening are.
Trinity College Dublin